The Association Between APOL1 Risk Alleles and Longitudinal Kidney Function Differs by HIV Viral Suppression Status
Identifieur interne : 000056 ( Canada/Analysis ); précédent : 000055; suivant : 000057The Association Between APOL1 Risk Alleles and Longitudinal Kidney Function Differs by HIV Viral Suppression Status
Auteurs : Michelle M. Estrella ; Man Li [États-Unis] ; Adrienne Tin [États-Unis] ; Alison G. Abraham [États-Unis] ; Michael G. Shlipak ; Sudhir Penugonda [États-Unis] ; Shehnaz K. Hussain ; Frank J. Palella [États-Unis] ; Steven M. Wolinsky [États-Unis] ; Jeremy J. Martinson ; Rulan S. Parekh [États-Unis, Canada] ; W. H. Linda Kao [États-Unis]Source :
- Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America [ 1058-4838 ] ; 2014.
Descripteurs français
- KwdFr :
- ARN viral (sang), Afro-Américains (génétique), Allèles, Apolipoprotéines (génétique), Charge virale, Facteurs de risque, Génotype, Humains, Infections à VIH (physiopathologie), Infections à VIH (traitement médicamenteux), Infections à VIH (virologie), Lipoprotéines HDL (génétique), Mâle, Prédisposition génétique à une maladie, Rein (physiopathologie), Taux de filtration glomérulaire (génétique), Thérapie antirétrovirale hautement active, VIH (Virus de l'Immunodéficience Humaine) (génétique), VIH (Virus de l'Immunodéficience Humaine) (physiologie), Études de cohortes, Études de suivi.
- MESH :
- génétique : Afro-Américains, Apolipoprotéines, Lipoprotéines HDL, Taux de filtration glomérulaire, VIH (Virus de l'Immunodéficience Humaine).
- physiologie : VIH (Virus de l'Immunodéficience Humaine).
- physiopathologie : Infections à VIH, Rein.
- sang : ARN viral.
- traitement médicamenteux : Infections à VIH.
- virologie : Infections à VIH.
- Allèles, Charge virale, Facteurs de risque, Génotype, Humains, Mâle, Prédisposition génétique à une maladie, Thérapie antirétrovirale hautement active, Études de cohortes, Études de suivi.
English descriptors
- KwdEn :
- African Americans (genetics), Alleles, Antiretroviral Therapy, Highly Active, Apolipoproteins (genetics), Cohort Studies, Follow-Up Studies, Genetic Predisposition to Disease, Genotype, Glomerular Filtration Rate (genetics), HIV (genetics), HIV (physiology), HIV Infections (drug therapy), HIV Infections (physiopathology), HIV Infections (virology), Humans, Kidney (physiopathology), Lipoproteins, HDL (genetics), Male, RNA, Viral (blood), Risk Factors, Viral Load.
- MESH :
- chemical , blood : RNA, Viral.
- chemical , genetics : Apolipoproteins, Lipoproteins, HDL.
- drug therapy : HIV Infections.
- genetics : African Americans, Glomerular Filtration Rate, HIV.
- physiology : HIV.
- physiopathology : HIV Infections, Kidney.
- virology : HIV Infections.
- Alleles, Antiretroviral Therapy, Highly Active, Cohort Studies, Follow-Up Studies, Genetic Predisposition to Disease, Genotype, Humans, Male, Risk Factors, Viral Load.
Abstract
HIV-infected African Americans who carry the
Url:
DOI: 10.1093/cid/ciu765
PubMed: 25281610
PubMed Central: 4318914
Affiliations:
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PMC:4318914Le document en format XML
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Abraham</name><affiliation wicri:level="2"><nlm:aff id="af2"><addr-line>Department of Epidemiology</addr-line>,<institution>Johns Hopkins University School of Public Health</institution>,<addr-line>Baltimore, Maryland</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Shlipak, Michael G" sort="Shlipak, Michael G" uniqKey="Shlipak M" first="Michael G." last="Shlipak">Michael G. Shlipak</name><affiliation><nlm:aff id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af4"><addr-line>Department of Epidemiology and Biostatistics</addr-line>,<institution>University of California</institution></nlm:aff></affiliation><affiliation><nlm:aff id="af5"><addr-line>Department of General Internal Medicine</addr-line>,<institution>San Francisco Veterans Affairs Medical Center</institution>,<addr-line>California</addr-line></nlm:aff></affiliation></author><author><name sortKey="Penugonda, Sudhir" sort="Penugonda, Sudhir" uniqKey="Penugonda S" first="Sudhir" last="Penugonda">Sudhir Penugonda</name><affiliation wicri:level="2"><nlm:aff id="af6"><addr-line>Department of Medicine, Northwestern University Feinberg School of Medicine</addr-line>,<addr-line>Chicago, Illinois</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Hussain, Shehnaz K" sort="Hussain, Shehnaz K" uniqKey="Hussain S" first="Shehnaz K." last="Hussain">Shehnaz K. Hussain</name><affiliation><nlm:aff id="af7"><addr-line>Department of Medicine</addr-line>,<institution>Cedars-Sinai Medical Center</institution></nlm:aff></affiliation><affiliation><nlm:aff id="af8"><addr-line>Department of Epidemiology, Fielding School of Public Health</addr-line>,<institution>University of California</institution>,<addr-line>Los Angeles</addr-line></nlm:aff></affiliation></author><author><name sortKey="Palella, Frank J" sort="Palella, Frank J" uniqKey="Palella F" first="Frank J." last="Palella">Frank J. Palella</name><affiliation wicri:level="2"><nlm:aff id="af6"><addr-line>Department of Medicine, Northwestern University Feinberg School of Medicine</addr-line>,<addr-line>Chicago, Illinois</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Wolinsky, Steven M" sort="Wolinsky, Steven M" uniqKey="Wolinsky S" first="Steven M." last="Wolinsky">Steven M. Wolinsky</name><affiliation wicri:level="2"><nlm:aff id="af6"><addr-line>Department of Medicine, Northwestern University Feinberg School of Medicine</addr-line>,<addr-line>Chicago, Illinois</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Martinson, Jeremy J" sort="Martinson, Jeremy J" uniqKey="Martinson J" first="Jeremy J." last="Martinson">Jeremy J. Martinson</name><affiliation><nlm:aff id="af9"><addr-line>Department of Infectious Diseases and Microbiology</addr-line>,<institution>University of Pittsburgh Graduate School of Public Health</institution>,<addr-line>Pennsylvania</addr-line></nlm:aff></affiliation></author><author><name sortKey="Parekh, Rulan S" sort="Parekh, Rulan S" uniqKey="Parekh R" first="Rulan S." last="Parekh">Rulan S. Parekh</name><affiliation><nlm:aff id="af1"><addr-line>Department</addr-line><addr-line>of Medicine</addr-line>,<institution>Johns Hopkins University School of Medicine</institution></nlm:aff></affiliation><affiliation wicri:level="2"><nlm:aff id="af2"><addr-line>Department of Epidemiology</addr-line>,<institution>Johns Hopkins University School of Public Health</institution>,<addr-line>Baltimore, Maryland</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Baltimore</wicri:cityArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af10"><institution>Hospital for Sick Children, University Health Network and University of Toronto</institution>,<addr-line>Ontario</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kao, W H Linda" sort="Kao, W H Linda" uniqKey="Kao W" first="W. H. Linda" last="Kao">W. H. Linda Kao</name><affiliation wicri:level="2"><nlm:aff id="af2"><addr-line>Department of Epidemiology</addr-line>,<institution>Johns Hopkins University School of Public Health</institution>,<addr-line>Baltimore, Maryland</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Baltimore</wicri:cityArea></affiliation></author></analytic><series><title level="j">Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</title><idno type="ISSN">1058-4838</idno><idno type="eISSN">1537-6591</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>African Americans (genetics)</term><term>Alleles</term><term>Antiretroviral Therapy, Highly Active</term><term>Apolipoproteins (genetics)</term><term>Cohort Studies</term><term>Follow-Up Studies</term><term>Genetic Predisposition to Disease</term><term>Genotype</term><term>Glomerular Filtration Rate (genetics)</term><term>HIV (genetics)</term><term>HIV (physiology)</term><term>HIV Infections (drug therapy)</term><term>HIV Infections (physiopathology)</term><term>HIV Infections (virology)</term><term>Humans</term><term>Kidney (physiopathology)</term><term>Lipoproteins, HDL (genetics)</term><term>Male</term><term>RNA, Viral (blood)</term><term>Risk Factors</term><term>Viral Load</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (sang)</term><term>Afro-Américains (génétique)</term><term>Allèles</term><term>Apolipoprotéines (génétique)</term><term>Charge virale</term><term>Facteurs de risque</term><term>Génotype</term><term>Humains</term><term>Infections à VIH (physiopathologie)</term><term>Infections à VIH (traitement médicamenteux)</term><term>Infections à VIH (virologie)</term><term>Lipoprotéines HDL (génétique)</term><term>Mâle</term><term>Prédisposition génétique à une maladie</term><term>Rein (physiopathologie)</term><term>Taux de filtration glomérulaire (génétique)</term><term>Thérapie antirétrovirale hautement active</term><term>VIH (Virus de l'Immunodéficience Humaine) (génétique)</term><term>VIH (Virus de l'Immunodéficience Humaine) (physiologie)</term><term>Études de cohortes</term><term>Études de suivi</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Apolipoproteins</term><term>Lipoproteins, HDL</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>African Americans</term><term>Glomerular Filtration Rate</term><term>HIV</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Afro-Américains</term><term>Apolipoprotéines</term><term>Lipoprotéines HDL</term><term>Taux de filtration glomérulaire</term><term>VIH (Virus de l'Immunodéficience Humaine)</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>VIH (Virus de l'Immunodéficience Humaine)</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>HIV</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Infections à VIH</term><term>Rein</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>HIV Infections</term><term>Kidney</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>ARN viral</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Alleles</term><term>Antiretroviral Therapy, Highly Active</term><term>Cohort Studies</term><term>Follow-Up Studies</term><term>Genetic Predisposition to Disease</term><term>Genotype</term><term>Humans</term><term>Male</term><term>Risk Factors</term><term>Viral Load</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Allèles</term><term>Charge virale</term><term>Facteurs de risque</term><term>Génotype</term><term>Humains</term><term>Mâle</term><term>Prédisposition génétique à une maladie</term><term>Thérapie antirétrovirale hautement active</term><term>Études de cohortes</term><term>Études de suivi</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>HIV-infected African Americans who carry the <italic>APOL1</italic> high-risk genotype had faster kidney function decline than persons with the low-risk genotype; this was most pronounced among those without sustained HIV suppression. Associations were not observed among those with sustained viral suppression.</p></div></front></TEI><affiliations><list><country><li>Canada</li><li>États-Unis</li></country><region><li>Illinois</li><li>Maryland</li></region></list><tree><noCountry><name sortKey="Estrella, Michelle M" sort="Estrella, Michelle M" uniqKey="Estrella M" first="Michelle M." last="Estrella">Michelle M. Estrella</name><name sortKey="Hussain, Shehnaz K" sort="Hussain, Shehnaz K" uniqKey="Hussain S" first="Shehnaz K." last="Hussain">Shehnaz K. Hussain</name><name sortKey="Martinson, Jeremy J" sort="Martinson, Jeremy J" uniqKey="Martinson J" first="Jeremy J." last="Martinson">Jeremy J. Martinson</name><name sortKey="Shlipak, Michael G" sort="Shlipak, Michael G" uniqKey="Shlipak M" first="Michael G." last="Shlipak">Michael G. Shlipak</name></noCountry><country name="États-Unis"><region name="Maryland"><name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name></region><name sortKey="Abraham, Alison G" sort="Abraham, Alison G" uniqKey="Abraham A" first="Alison G." last="Abraham">Alison G. Abraham</name><name sortKey="Kao, W H Linda" sort="Kao, W H Linda" uniqKey="Kao W" first="W. H. Linda" last="Kao">W. H. Linda Kao</name><name sortKey="Palella, Frank J" sort="Palella, Frank J" uniqKey="Palella F" first="Frank J." last="Palella">Frank J. Palella</name><name sortKey="Parekh, Rulan S" sort="Parekh, Rulan S" uniqKey="Parekh R" first="Rulan S." last="Parekh">Rulan S. Parekh</name><name sortKey="Penugonda, Sudhir" sort="Penugonda, Sudhir" uniqKey="Penugonda S" first="Sudhir" last="Penugonda">Sudhir Penugonda</name><name sortKey="Tin, Adrienne" sort="Tin, Adrienne" uniqKey="Tin A" first="Adrienne" last="Tin">Adrienne Tin</name><name sortKey="Wolinsky, Steven M" sort="Wolinsky, Steven M" uniqKey="Wolinsky S" first="Steven M." last="Wolinsky">Steven M. Wolinsky</name></country><country name="Canada"><noRegion><name sortKey="Parekh, Rulan S" sort="Parekh, Rulan S" uniqKey="Parekh R" first="Rulan S." last="Parekh">Rulan S. Parekh</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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